GENOME-WIDE DISCOVERY OF DRUG-DEPENDENT HUMAN LIVER REGULATORY ELEMENTS.

Inter-individual variation in gene regulatory elements is hypothesized to play a causative role in adverse drug reactions and reduced drug activity.However, relatively little is known about the location and function of drug-dependent elements.To uncover drug-associated elements in a genome-wide manner, we performed RNA-seq and ChIP-seq using antibo

The benefits of functional electrical stimulation during cycling (FES-cycling) have been ascertained following spinal cord injury.The instrumented pendulum test was applied to chronic paraplegic patients to investigate the effects of FES-cycling of different duration (20-min vs.40-min) on biomechanical and electromyographic characterization of knee